Hipertenzija u budućnosti. inPharma - Antihipertenzivni sastojci
The mechanisms of hypertension associated with obesity include sodium retention, sympathetic and renin-angiotensin-aldosterone hyperactivity, insulin resistance, reduced nitric oxide activity and vascular endothelial dysfunction.
It is mandatory to determine blood pressurein all adipose patients. Also, obesity should be evaluated in all patients with hypertension.
While measuring the blood pressure in obese patient, an adequate cuff that fits the upper arm should hipertenzija u budućnosti used. Even a moderate weight loss in adipose patient with hypertension can significantly reduce blood pressure and has a beneficial effect on the metabolic profile.
Although long-term weight loss will lead to decrease of blood pressure, it is not recommended to wait for the patient to lose weight in order to eventually lower the blood pressure in the future.
Loss of body weight in hypertensive adipose patients should be encouraged, while the hypertension should be treated with antihypertensive drugs as well with non-pharmacological interventions aimed to reduce body weight. Key words:.