Do hypertensive kardio aterosklerotske s hipertenzijom diabetic patients also benefit from statin therapy?
Izvleček: The risk factors for cardiovascular diseases CVD include hypertension, diabetes and dyslipidemia. Therefore, the modern guidelines for CVD preventionsuggest several steps to reduce these risk factors, including pharmacological treatment. Numerous clinical studies demonstrated benefits of cholesterol level reduction in hypertensive patients.
It was shown that concomitant treatment of hypertension and dyslipidemia significantly reduced CVD risk in comparison with blood pressure or blood cholesterol reduction alone. Clinical studies with Krkaʼs atorvastatin also demonstrated the efficacy and safety of lipid-lowering therapy in hypertensive patients with dyslipidemia. It is well known that the risk for atherosclerotic cardiovascular disease in diabetic patients is increased two to fourfold.
Clinical studies demonstrated that statin treatment was also beneficial in diabetic patients. Similarly, sub-analyses of studies in diabetic patients treated with Krkaʼs atorvastatin proved the advantages of such treatment, as well as its safety.
Thus, reducing high blood cholesterol levels in hypertensive and diabetic patients clearly brings additional benefits for the patients.
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